Psilocybin is a unique compound, but it is part of a larger family of natural tryptamines that are also psychedelic or otherwise psychoactive. This presentation will explore the tryptamine 'family' and the chemical diversity of these compounds in plants, animals and fungi. We will discuss the origin and distribution of tryptamines in nature. We will also discuss some synthetic analogs of psilocybin or other tryptamines. If you are a chemist, you will enjoy this overview of tryptamines. If you are not a chemist, you may be baffled at times but you will still enjoy it!